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It is very marked during the tumour-induced angiogenic switch that accompanies the passage from an in situ lesion to invasive cancer.
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"It was very marked, and pretty immediate," said Dr. Robin M. Whyatt, the principal author of the study and an assistant professor at the Mailman School of Public Health at Columbia.
"One important one is that women who do shift work have fewer children - the pattern is very marked, and it matters to ovarian cancer even more than breast cancer".
The drop in defamation claims is very marked indeed.
"Mexico is a patriarchal society and the underlying classism is very marked.
In addition, statistics indicate that the effect of early environment and innate dispositions on later functioning is very marked.
This may or may not help to explain the enormous passion for biographies and autobiographies which is very marked here.
The relation of house to garden is very marked, in the illustrations of the Deepdene that survive.
Why this should be in a theatre with such an overwhelming, colourful presence I don't know, but the effect is very marked.
The predominance of the double-ended, lapstrake hull in Scandinavia is very marked, and some modern boats strongly resemble those of the Vikings.
Social stratification is very marked at settlement sites such as El Argar and El Oficio (Almería), where the richest women were adorned with silver diadems while their male consorts were equipped with bronze swords, axes, and polished pottery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com