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99 It is, therefore, rational to evaluate the effect of combining lifestyle modification with pharmacological therapies aimed to mitigate the biological pressure to weight regain.
It is therefore rational to venture that the screening of TAM activation in breast cancer patients could be useful in predicting patients with a high metastatic risk.
It is therefore rational to predict that the further upregulation of HIF-1 α by an anaesthetic would compound or even enhance its effect of promoting malignant behaviour in cancer cells, whereas the use of an agent such as propofol which has been shown to inhibit HIF-1 α activity might prove helpful in bringing about the opposite effect.
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It was therefore rational to expand the use of CRS and IPC to PC from colorectal cancer, notwithstanding the less favourable disease biology.
It is therefore perfectly rational for poor people to try to move to rich countries (the author writes sympathetically of the "paper-burners" trying to enter Europe from North Africa).
Components of the IL-6 signalling pathway are, therefore, rational targets for the treatment of sJIA.
It is therefore envisaged that a rational design and engineering of the biogas-producing microbial community is possible.
As Macve (1981, p.22) states: "Anyone recommending a particular [CSR] practice must necessarily base his views on an implicit conceptual framework - and it is therefore important, if there is to be rational discussion and evaluation of the proposal, to try and make that framework explicit".
27 It is therefore of much interest to develop a rational approach to identify drug combinations that exhibit antagonistic and, in particular, suppressive interactions that can bias selection against resistance.
Severely afflicted patients more often require hospitalization, and the rate is therefore more rational.
The CXCR4 gene plays a major role in progression and metastasis of various tumor types and is, therefore, a rational target for breast cancer therapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com