However, in terms of the cartilage T2* and T1Gd quantification, this averaged spatial measurement is substantially relevant in regions where the cartilage damage is confined to a rather small area.
In addition, the response patterns of the participants do not present problems that would be substantially relevant, i.e., χ2 greater than 3.0.
Marked distinctions between the standard and intervention approaches were the assertiveness, the accessibility, and the active assistance of patients to scheduled appointments in the intervention group; these parts were all thought to be substantially relevant for this patient group.
Now, it is substantially unchanged.
Adjusted for inflation, it is substantially lower.
Today, it is substantially less than 2%.
And yes, it's substantially better.
Second, they are totally robust, i.e., their convergence speed is substantially independent of all the relevant parameters: in our case, these are the matrix size (related to the fineness parameter), the spline degree (associated to the approximation order), and the dimensionality d of the problem.
This study suggests that the rate of clinically relevant SREs is substantially lower than the event rate observed in phase III clinical trials.
On the other hand, when the anti-TNFα drug effect is analysed in patients with previously insufficient responses to MTX, the relative effect is substantially larger (2.32 [1.99–2.72]) and both clinically relevant and statistically significant [NNT of 4 (3–5)].
Hence, the risk of overlooking important relevant protein families is substantially reduced due to the availability of different environmental conditions, with the ultimate proof being the genome sequences of these two distantly related glaucophytes.
