The First Amendment has wandered far from its purposes when it is recruited to protect commercial automatons from regulatory scrutiny.
However, the exact function of Ash1L and how it is recruited to its targets are poorly understood.
Its recruitment to patches is shown to depend on its N-BAR domain, suggesting it is recruited to the membrane curvature observed in detail by SEM in these patches.
In cadherin-mediated cell-cell adhesions, vinculin may have a role similar to its role in FAs, where it is recruited in a force-dependent manner to increase stability [ 45].
It is recruited to phosphorylated EGFR through its SH2 domains, where it serves as a substrate for EGFR kinase activity.
52 However, in the presence of upregulated RAS (occurring through mutation in RAS 47 or an upstream activator of RAS), inhibition of V600-BRAF by a selective inhibitor releases it from its autoinhibited state in the cytosol and it is recruited to the plasma membrane where it dimerizes with CRAF, enhancing the activation of CRAF and allowing CRAF to hyperactivate the signaling pathway.
Although STIM2β does not by itself strongly bind Orai1, it is recruited to Orai1 channels by forming heterodimers with other STIM isoforms.
It is recruited to damaged chromatin as a component of the BRCA1-A deubiquitinase, which cleaves K63-linked ubiquitin chains attached to histone H2A and H2AX.
You could argue that he is meditating wrongly, but I think his testimony shows that the effect of any practice, meditation included, depends on the ends to which it is recruited.
We focus here on the properties of the αC-Helix showing 1) how residues communicate with different parts of the molecule, 2) how it is recruited to the active site as a consequence of assembling of the R-spine, and 3) how it is regulated by linkers/motifs/proteins that lie outside the conserved kinase core.
Distinct from USP4, USP15 was not found to bind to activate TβRI directly; rather, it is recruited to the active receptor by SMAD7.
