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"To try to minimise the risk of type-2 diabetes as much as possible it is reasonable to reduce fruit juice consumption and increase consumption of whole fruits".
To improve residents' health, it is reasonable to reduce the night workload as much as possible, unless this could compromise patient safety or quality of care [ 8].
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Vasodilator and/or beta-blocker therapy to maintain MAP ≤100 mmHg is reasonable to reduce myocardial afterload and oxygen demand in patients who remain hypertensive after adequate sedation [ 9].
It would be reasonable to reduce the drug dose to the lowest level that would still be effective.
We aimed to establish whether it would be reasonable to reduce current levels of out-of-hours (OOH) medical cover in cardiac ICUs (CICUs) based upon current UK practice.
It can be reasonable to reduce the complexity of an environmental sample by enrichment or size selection, in particular when multiple different enrichments or samples with different size fractions are taken and their results are combined, but such effects need to be taken into account in experiment design and interpretation of the final data.
Moreover, our ranking methodology was reasonable to reduce false positive identifications because our predicted structures that matched with validated compounds all resulted in high rankings.
MAP target as low as 60 mmHg may be reasonable to reduce vasopressor requirement.
Therefore, in clustering of pyrosequencing data having higher error rate than Sanger data, the use of a cutoff identity lower than 97% and a lower number of reads are reasonable to reduce overestimation of the OTU number.
A single dose of PQ could contribute to reducing malaria transmission through its effects on mature gametocytes, and it is reasonable to assume that reducing the density and duration of gametocytes in the blood of infected patients will reduce the duration of potential infectiousness to mosquitoes at the level of the individual (see Figure 1).
While it is reasonable to assume that reducing the expression of a TCA cycle intermediate could slow metabolic activity sufficiently to reduce growth rate, citrate accumulation is also thought to be a principle culprit for growth retardation in aconitase deficient mutants [ 40- 43].
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