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For an inclusive approach of ERA to be compliant with the EU regulations, it is reasonable to begin this process by defining and describing the 'case' to be assessed.
Thus, when palliative treatment is the objective, it is reasonable to begin with monotherapy and then to consider a second line of polychemotherapy after progression.
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Taking into account the presence or absence of severe ocular defects, depending on the origin of the patient, it might be reasonable to begin the mutational analysis with a study of frequent disease-causing mutations.
With unemployment at just 3.5%, it is reasonable to assume that wages might soon begin to rise.
It is reasonable to hypothesize that these disruptions may begin in infancy with impairments in maternal-infant bonding.
It is reasonable to assume that these dimensions would begin to take shape more quickly or efficiently than the others at the start of any integration project and, as such, would lay the foundations for such projects.
Letter 1 begins "It is reasonable to suppose that in remote ages this woody and mountainous district was inhabited only by bears and wolves".
However, it is reasonable to conclude that many physiotherapists had begun to recognise the importance of the biopsychosocial model in back pain care prior to the NICE guideline, with research revealing the possible connection between patients' psychosocial factors and clinical outcomes [ 28- 32].
Since most diseases likely have a long prodromal phase, it is reasonable to postulate that causative biochemical perturbations would begin to appear well before the clinical onset of symptoms.
They say it is reasonable to conclude that those with service-connected PTSD began suffering its ill effects while still in uniform.
Because the TK-Neo cassette used to generate the VAChTFloxNeo allele was introduced 450 bp upstream from the beginning of M-exon, it is reasonable to suggest that its presence interfered with the function of additional regulatory elements.
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