Exact(3)
It is primarily recognized as a tumor suppressor (47), but germline mutations in it and other genes involved in the Ras/MAPK pathway can also cause various developmental disorders collectively known as the neuro-cardio-facial-cutaneous (NCFC) syndromes or 'RAS-opathies' (48).
While the Tg lesion is a substrate for the UvrABC NER repair system of Escherichia coli 64) and is excised from DNA in vitro by human NER enzymes (65), it is primarily recognized as a substrate for base excision repair, both in E. coli and in mammalian cells (49).
Although it is primarily recognized as the master transcription factor in Th1 cell development, T-bet is now known to be expressed and have a key role in cells of both the adaptive and innate immune systems (Garrett et al., 2007, 2009; Lugo-Villarino et al., 2003; Szabo et al., 2000, 2002; Townsend et al., 2004), but it has no known role outside the immune system.
Similar(57)
Tai Chi (Chinese) - This is actually a mixed art, with both Hard and Soft elements, but is primarily recognized for its Soft elements.
Endogenous melatonin is primarily recognized for regulation of the sleep wake cycle, but at high doses, it has potent antioxidant activity and is able to enter all cell compartments including mitochondria.
Zinc is primarily recognized in biology as a structural protein folding element found in zinc finger motifs, however it has many other cellular functions.
Translational science is primarily recognized as an important contributor to product development.
The fibrillin peptide, to our knowledge, is the first identified autoantigen that is primarily recognized in polyarticular JIA patients.
'Gastric stump carcinoma' is primarily recognized as a carcinoma developing in the gastric remnant after gastrectomy for benign disease (Freedman and Berne, 1954; Heinzel and Laqua, 1954).
The envelope protein (E) of dengue virus binds to receptors present on the host cells through its domain III that has been primarily recognized to bind cell receptors.
Many invasive plant species in Europe are primarily recognized as agricultural or forestry weeds.
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