Instrumented indentation tests are often suitable to get information about the elastic plastic behaviour, where the indentation depth is measured as a function of indentation force.
Nevertheless, such mean data is often suitable for many applications either in itself [ 4, 5] or as additional data to support experiments at the single-cell level.
The chemical reaction kinetics have been implemented using a quasi-homogeneous approach which is often suitable for the heterogeneous catalysis.
For the analysis of a prognostic marker study, we consider multivariable regression models as the method of choice, such as the Cox model, which is often suitable for survival-type data that arises from prognostic studies.
Nonetheless, for large studies with many samples, a preliminary screen using this method is often suitable for identifying large-scale shifts in microbial community structure and for identifying statistically significant changes in the relative abundance of organisms between groups or treatments.
However, in practice, it is often difficult to collect suitable materials for codigestion with the feedstock of interest, so the operation of SS-AD is difficult to guarantee.
Unlike cytotoxic anticancer drugs, the mechanism of cancer immunotherapies is mediated by the immune response, and thus it is often difficult to establish suitable animal models.
If the exposures are intermittent and the biomarker is short-lived, it is often difficult to collect suitable samples for biomonitoring.
Currently, due to the increasing numbers of simulation software packages available in the market, it is often challenging to choose a suitable package that meets users' demands.
Fortunately, these assumptions are often valid in clinical data, and where they are not true of the raw data it is often possible to apply a suitable transformation.
