Sentence examples for it is often particularly difficult from inspiring English sources

It is often particularly difficult to identify the causal variant under the quantitative trait loci (QTL).

This is especially important in neurodegenerative diseases, as it is often particularly difficult to accurately establish the early stages of these disorders [ 10].

For example, it is often particularly difficult to separate natural selection on pollen (with a primary function to fertilize the ovules) from that of sexual selection (the ability to fertilize the ovules ahead of pollen from other mates) (Moore and Pannell 2011).

Chronic musculoskeletal pain arising from conditions such as arthritis and rotator cuff disease is often particularly difficult to treat.

The RTW process is often particularly difficult for employees' with mental disorders due to various aspects of the severity of the individuals' mental health problems: the duration of the problems prior to the occurrence of sick leave or seeking help, and the level of symptoms (somatisation, anxiety and depression) [ 40].

Negotiations that involve the use and interpretation of scientific information and assessment are often particularly difficult, especially when the scientific input is uncertain or contested.

However, other studies have shown that the more participants know about the trials, the more willing they are to volunteer., Long-term follow-up and high retention rates are often particularly difficult to achieve when subjects are homeless or live in temporary housing, with no formal address or telephone and few resources to travel to health centers.

In low-income countries, it is often difficult to obtain representative samples, particularly when hidden and vulnerable population groups are involved [ 35, 36].

Experimentally, there are many attempts to correlate specific components of the emission with the presence or deficiency of specific constituents, particularly oxygen, but it is often difficult to make definitive assignments.

This is particularly relevant as it is often difficult to deliver full does of combinations of MEK and PI3K pathway inhibitors in the clinic [ 16].

It is often difficult to tell what traits are fitness components, particularly for microbes, which are difficult to study in a natural environment.