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In fact, it is not difficult to conceive of mereological scenarios that violate not only (P.4), but also (P.4b) and even (P.4a).
For example, it is not difficult to conceive how a sessile compound eye can be altered into a stalked eye of the same basic design (say, apposition), but it is more problematic to see the evolutionary route from apposition to reflecting superposition.
It is not difficult to conceive of such systems as including multiple, nested sub-systems.
It is not difficult to conceive that PRG48T/L89M exhibits decreased susceptibility to SQV given that HIV-1 PR mutants containing Gly48Val or Gly48Val/Leu90Met demonstrate 13.5- and 419-fold reductions of susceptibility to SQV, respectively.
Clearly, it is not difficult to conceive how the macrovascular risk factors in diabetes would contribute to cerebrovascular damage [ 12], while chronic hyperglycemia may lead to the accumulation of advanced glycation end-products in the brain [ 68] and the development of small vessel ischemic change.
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Still, experts say it's not difficult to conceive.
Because these works were often absent sustained reflection on the cross, usually lacked a coherent narrative, and sometimes contained rather peculiar theological assertions, is not difficult to conceive that they rarely caught hold of the imagination of early Christian congregations.
Not much has been confirmed yet about these young women's period of captivity, but it's not difficult to imagine what happened to them, since one of them has a six-year-old daughter conceived during her captivity.
It's not difficult to fathom why.
And it's not difficult to do.
It's not difficult to be sustainable.
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