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While the decision is largely practical, it is also symbolic.
The reason for this is largely practical: it is difficult to purify Mcm2-7 or the CMG complex in amounts large enough to perform these screens, and in vitro helicase activity has not been demonstrable for the whole complex until fairly recently [ 23, 113].
Their enthusiasm is largely practical.
For others, the appeal is largely practical.
Plumbing is largely practical, involving the repair, installation and main tenance of drainage, water supply and heating systems.
This is largely practical work, however.
The public health teaching required for such a course is largely practical, and requires involvement of public health branches of the health department, both national and provincial, plus travel to rural areas for practical experience of public child health programs.
It is likely that meeting will be largely practical and an assessment of what is known, as opposed to any ministerial political action.
The reasons were largely practical.
Whereas major challenges undoubtedly remain, particularly regarding data handling and the functional classification of variants, we suggest that these will be largely practical and not conceptual.
"If there is any practical application, then it is largely educational," Braben said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com