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It is hypothesis based in the sense that its critical aspect is to specify the hypothesized basis for using information at hand to infer the existence of the ability of an agent to cause human health impact.
In the latter, the information is structure-centric whereas in SOHN it is hypothesis centric.
It is hypothesis generating.
It is hypothesis that reactivation of VZV triggers some immunologic mechanisms, such as tissue antigen alteration or antigenic stimulation, which could result in cancer [ 41].
The main advantage of this method is that it is hypothesis free because it does not rely on current understanding of the pharmacokinetics and -dynamics of a drug.
The reason for bringing quantitative trial data together with qualitative evidence on patients' views is not to demonstrate a causal link; rather it is hypothesis generating by providing possible explanations for variation between trial findings.
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The Culverhouse et al. replication project is not discovery science, it is hypothesis-testing science.
Since this was a post hoc analysis, at best it is hypothesis-generating.
It actively proposes principled accounts of the phenomenon it investigates that is, hypotheses.
It is a hypothesis to support the hypothesis that sun exposure causes melanoma, he says.
It is therefore hypothesis generating rather than hypothesis testing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com