While the weight of evidence suggests that these allosteric modulators interact with different binding sites, it is important to consider that until the binding pockets for each of these compounds is fully elucidated, it is impossible to definitively determine whether these compounds bind to the same or distinct binding sites.
It has not been fully elucidated if in fact presentations of higher quality are more likely to have a subsequent full-text publication.
However, it has not been fully elucidated whether non-neuronal cells sense and respond to CO2.
So far, however, it has not been fully elucidated how activation of this pathway is translated into a morphological change.
It remains to be fully elucidated how long the effect of low-dose CY on Treg lasts for.
However, it has not been fully elucidated whether hypomagnesemia is a predictor of end-stage renal disease (ESRD) in type 2 diabetic nephropathy.
It remains to be fully elucidated whether an additional beneficial effect of combining beta-blockers and statins, compared to beta-blocker monotherapy, is a true pharmacological effect.
Vitamin D deficiency is now recognised as a common health problem associated with various chronic diseases; however, it has not been fully elucidated among the minority groups.
Still, it remains to be fully elucidated whether an additional beneficial effect of combining beta-blockers and statins, compared to beta-blocker monotherapy, is a true biological effect.
Although SPARC was reported to be upregulated by TGF-β or angiotensin II in several types of fibroblast [ 21, 22], it has not been fully elucidated whether other factors, associated with the progression of pulmonary fibrosis, upregulate SPARC expression.
It would not be fully elucidated whether choroidal thickness changes may affect MBR values, although the effect of choroidal thickening on MBR is estimated to be minimal or negligible compared to the extent of the MBR changing ratio [ 20].
