However, it is difficult to assign the enhancement of its effects to targeting of the hypoxic cells because of the significant level of its hypoxia-independent toxicity.
The word, a British gastronome wrote a hundred years ago, has been extended "so widely by the fancies and tastes of cooks that it is difficult to assign any limitation to its application".
Care is widely dispersed, so it is difficult to assign responsibility to one doctor.
Martin Straka and Martin Rucinsky will be free agents, and it is difficult to assign them a value.
She knows that it is difficult to assign blame for her family's many health problems.
While it is difficult to assign crisp classification values to measurands based on complex overlapping sensory signals, fuzzy logic offers a possibility to mathematically model such systems.
Appraisals of the property varied widely, Mr. Guldi said, mainly because it is difficult to assign a value when nothing like it has been sold in years.
But it is difficult to assign credit for one proposal or another to one side or the other because the two sides exchanged drafts over several weeks.
While assigning values to provisioning services is relatively straightforward, it is difficult to assign values to non-consumptive services like cultural services (Sukhdev, 2011).
Since temporal resolution in fMRI is low, it is difficult to assign local brain activations to these subprocesses with traditional analysis.
Serum linoleic acid was markedly elevated in DIO rats regardless of treatment, therefore it is difficult to assign a specific role of this FFA.
