Sentence examples for it is critically required from inspiring English sources

It is critically required to develop a solution to recycle and reuse these potential resources.

vacuole in MFs, where it is critically required for mycobacterial survival (Jayachandran et al, 2007).

Since then, UTX has been proven essential during normal development, as it is critically required for correct reprogramming, embryonic development and tissue-specific differentiation.

Importantly, IFN-γ has been shown to play a pivotal role in tumor-protective immune responses (Weiss et al., 2011): it is critically required for the "productive" immune surveillance of spontaneous malignancies and chemical carcinogen methylcholanthrene (MCA -induced sarcoMCA -inducedmemory formation, and esarcomasy senescence of cancer cells (Braumüller et al., 2013).

Altogether, the data show that Y1057 of VEGFR-2 is a major c-Src binding site on VEGFR-2 and its presence is critically required for VEGFR-2 to activate c-Src.

It is well known that PPARγ is critically required for white adipogenesis, PPARγ2 (instead of PPARγ1) being the more potent adipogenic isoform in vivo (61– 61).

Although it has been well established that PS exposure on apoptotic cells is critically required for their proper uptake, the identification of a single dominant receptor that is capable of recognizing and removing the apoptotic cells has remained controversial.

It appears that oxidation at the conserved cysteine residue (Cys106 in HsDJ-1) is critically required for DJ-1 function [ 22, 37- 39].

While JNK is critically required for neoplastic overgrowth in cooperation with NACT, as it is for RasACT, JNK can also restrain N-driven overgrowth and the loss of Scrib can help overcome the JNK-dependent restraint through aPKC-dependent pathways.

Thus, it appears that the different PKC isoforms have contrasting roles in platelet α-granule secretion: PKCα is critically required for α-granule secretion, and PKCθ acts to counter this action.

Mcl-1 is critically required for the development and maintenance of many cells of the hematopoietic system and it is sufficient to take away Mcl-1 in mature lymphocytes to induce apoptosis.