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In order to confirm the important biological activity and evaluate its therapeutic potential, it is critical to characterize the properties of the enzyme using the purified protein.
To understand how the CHD7 proteins achieve its function and how mutation of CHD7 leads to developmental disorders, it is critical to characterize WT and mutant CHD7 proteins biochemically.
It is critical to characterize the effects of various designs on engine performance and emissions.
Thus, it is critical to characterize the parameters related to the longwall mining process and to propose a general casing design guideline in such areas.
Because coal properties vary across the basin, it is critical to characterize injection site coals to best predict the potential for CO2 injection and storage capacity.
Thus, it is critical to characterize and dissect the anti-tumoral effect of hHSS1.
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Meso-scale structure is critical to characterize complex systems in chemical engineering.
Consequently, an analysis only focused on the Ramachandran dihedrals, ϕ and ψ, would have missed one of the main features of the structural landscape that is critical to characterize the relation between structure and energetics.
Quantitative evaluation of slip parameters (i.e., slip velocity, rise time and slip distance) of past slip events at shallow, tsunamigenic part of the fault is critical to characterize such earthquakes.
The slip coefficient is critical to characterizing gas permeability in Eq. 34.
Understanding controls on silicate weathering is critical to characterizing critical zone evolution.
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