We show that the number of abasic sites is significantly increased when the 3-methyladenine DNA glycosylase (Mag): AP endonuclease (Apn1) ratio is increased and that spontaneous frame shift mutation is considerably elevated when either Mag, or Mag plus Apn1, expression is elevated.
The risk for all forms of cardiovascular disease (CVD) is considerably elevated in patients with diabetes mellitus, and this is driven in part by the high prevalence of dyslipidemia in this population [ 2].
Incidence of IC is considerably elevated among the extremes of age, with high rates observed both in the elderly and in premature newborns in neonatal intensive care unit (NICU) [ 8– 10].
It is well established that tissue, cellular and serum copper levels are considerably elevated in various malignancies.
In the transition from the gametophytic to the protoplast stage, expression levels of genes involved in auxin signaling are considerably elevated.
Given the powerful and long-lasting impact from Harvey and the large contribution from Hurricane Irma, landfall ACE is likely to be considerably elevated for the 2017 hurricane season.
In the last (δ-β-thalassemia), Hb F concentrations usually are considerably elevated since the number of β-chains available to combine with α-chains is limited and γ-chain synthesis is not impaired.
Performance time and overall workload remained relatively stable, yet the number of chess moves made, time pressure and surprise recall performance were considerably elevated in the distributed planning condition.
When defects occur in both δ- and β-chain synthesis, causing δ-β-thalassemia, the concentrations of a type of hemoglobin known as Hb F usually are considerably elevated since the number of β-chains available to combine with α-chains is limited and γ-chain synthesis is not impaired.
After rapid desiccation of T. ruralis O(2) consumption upon rehydration was considerably elevated, and for up to 24 hours.
However, as compared to the least materially deprived neighbourhoods, rates were considerably elevated in the most materially deprived neighbourhoods.
