Sentence examples for it is considerably difficult from inspiring English sources

Both results of experiments and simulations show that it is considerably difficult to cover the small-angle corner entirely with liquid film.

However, the potential and the expectation raised by this technology is such that it is considerably difficult to keep track of the most significant progresses being now published in different and even monographic journals.

In PFC3D, it is considerably difficult to determine the appropriate values of meso-level parameters of particles because the values cannot be directly obtained by laboratory tests, field measurements or theoretical calculations.

On the other hand, the dimension of the data range has long been limited to 1, since it is considerably difficult to track the change in the inverse image in terms of multiple function values simultaneously.

Since the techniques on electromagnetic countermeasure (ECM) and counter-counter measures (CCM) are developing more and more sophisticated, we can foresee that it is considerably difficult to fulfil the goal of giving the most accurate interpretation about what the target is at any given point in time for any detection and recognition system.

However, it is considerably difficult to develop these glycolipids into the practical separation ligand due to their limited amounts.

It has been estimated that complete intubation of the colon is considerably difficult in up to 10-20% of procedures [ 23].

Disruption of CRP-LOX-1 interaction is also an attractive target, although it would be much more challenging since inhibition of protein-protein interaction with small-molecule compounds is considerably difficult [ 158– 160].Further studies are necessary to investigate the binding modes of each ligand to LOX-1, and which of the ligand interactions underlies the specific disease phenotypes.

However, complete elimination of all antigens is considerably difficult to perform and verify (Malone et al. 1984).

Diagnosing IFT is considerably difficult because of the nonspecific clinical manifestations and the low yields in microbiological tests [2, 11, 12].

However, the procedure of laparoscopic surgery is considerably difficult for surgeons, thus paving the way for the introduction of robotic technology to reduce the surgeon's burden.