Thus, it is conceivable to suggest that the observed decrease in epithelization and increase in wound contraction with application of the extract could be due to the plant's potential to increase collagen synthesis through its effect on hydroxyproline content, as wound contraction begins almost concurrently with collagen synthesis [ 1].
RANKL can stimulate osteoclast survival, activation, and differentiation, so it is conceivable to infer that increased level of RANKL may cause a decrease in BMD.
Now, it is conceivable to produce nearly any organic molecule of interest using a cellular host.
Therefore, it is conceivable to test the role of VDAC1 in myostatin-induced apoptosis.
It is conceivable that decreased levels of RIP140 serve as a compensatory mechanism to favour energy expenditure to reduce fat accumulation.
As inactivation of Ap4 led to a decrease in the number of ISCs and an increase in Paneth cells, it is conceivable that the decreased formation of adenomas in the absence of Ap4 is due to the smaller number of bona-fide ISCs that are able to initiate adenomas after acquiring further genetic and epigenetic alterations.
Though toxicity in terms of grade 3 4 hematologic adverse events was lower using the AZA-5 than the AZA-5-2-2 regiten, 63 is is conceivable that a decreased dose may also translate into reduced efficacy in higher-risk MDS patients.
It has previously been shown that exogenous gliotoxin exposure to both A. fumigatus wild-type and ∆ gliT results in decreased GSH levels [ 5] and so it is conceivable that this decrease in cellular GSH could impact on iron homeostasis or iron sensing.
The authors do not discuss the relevance of this depletion, but it is conceivable that this decrease allows efficient keratinocyte migration and proliferation during wound repair.
It is conceivable that most anaesthesia will decrease clearance of radiotracers from the body and give rise to a systematic increase in hypoxia levels within tumours.
Assuming that the malignant tumor is the primary source of increased OPN plasma concentration, it is conceivable that an early decrease in OPN plasma levels may be observed after surgical removal of the tumor whereas with radiotherapy, tumoricidal effects are not as instant since tumor shrinkage occurs over the whole treatment course and tumor regression continues after the end of radiotherapy.
