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Screening indications are self-reported cognitive dysfunction or suspicion for dementia by caregivers or relatives, but it is challenging to detect dementia in its early stages.
Due to the potential low resolution and noise, it is challenging to detect such features.
Thus it is challenging to detect these hormones in saliva [ 1, 2].
As pointed out in the introduction, it is challenging to detect the ST segment and especially the J point in ECG analysis.
Several methods are available to study DNA methylation such as bisulphite treatment, HPLC, and microarrays, although it is challenging to detect 6 mA methylation patterns using any of these methods [ 43].
It is challenging to detect interaction effects among multiple pollutants using standard/generalized linear regression, so it is expected the DSA algorithm proposed for genomic data could be borrowed to address this problem.
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Since the basal expression level of the pMLPm promoter is low, it was challenging to detect significant repression from this promoter.
To the best of our knowledge, this asymmetry is not seen in tsunami observations, though it might be challenging to detect if the initial (v_0 x)) is rather small and bathymetric effects complicate the tsunami waveform.
Together, due to many sources influencing lysoPC concentration in blood, which may depend on the individual's genotype and lifestyle, it may be challenging to detect disease-specific changes of lysoPCs in the general population, such as in our recent study in a general population cohort [ 27].
Fractures of the pubis may be challenging to detect using our method in its current form, as the superior ramus and inferior ramus can break into two separate parts.
The magnitude of these effects varied widely, from a small, slow process that would be challenging to detect, to a large, rapid response that could be an environmental catastrophe.
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