Sentence examples for it is challenging to construct from inspiring English sources
As the experimental structures of KCNQ2 and its complexes with other ligands have not been determined, it is challenging to construct a structural model for the ztz240-KCNQ2 interaction.
It is challenging to construct a reliable numerical algorithm to accurately capture the non-equilibrium physical effect in different regimes.
However, even if sufficient data are available, it is challenging to construct a model of cell signalling to explain the data and make accurate predictions.
Robust, programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources are challenging to construct.
SDM is a multi-dimensional construct, which is challenging to evaluate.
Quality of life (QOL) is a complex, multifaceted construct that is challenging to accurately measure.
While it is a challenge to construct many suitable transformation functions for the costs with diverse units, this paper designs a heterogeneous-cost sensitive learning (HCSL) algorithm to make split attribute selection more effective.
Although individual graphene nanoribbons have been produced by longitudinal unzipping of carbon nanotubes or patterned growth in large scale, it is still a challenge to construct these unique structures into macroscopic functional architectures using a cost-effective method.
Systems approaches have long been used in pharmacology to understand drug action at the organ and organismal levels using experimental and computational approaches It would be great challenges to construct a computational model of a multi-level for understanding drug action and discovering drug with the lack of multi-level data.
"On the basis of very limited data, it is a real challenge to construct an accurate and robust model of hedge-fund returns," Brown said.
Given that it is a major challenge to construct an isochronal foliation we use non-isochronal phase-amplitude coordinates as a practical method for obtaining a more accurate description of neural systems.
