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Given that the numerical approach is valid for all concentration values and solves the full model (2)– (6), it is appropriate to validate results of the analytical model against numerical solutions.
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The score performed well against other prognostic staging systems for HCC despite its simplicity, and has been validated on an independent dataset, but it is appropriate to prospectively validate it on a larger cohort to confirm our findings.
As with any new strategy for approaching biochemical (or other) problems, it is appropriate to calibrate or validate it by applying it to a well-understood system.
For this paper, we decided that it would only be appropriate to attempt to validate the PIPP Impact subscales at this stage for use in the Thai sample, and not the Distress subscales.
Therefore, should disasters survivors be viewed as "psychologically damaged by the experiences that befell them or was it more appropriate to validate the experience of trauma from a humanistic and existential perspective by viewing their responses as an adaptation to frightening environmental events?" [ 12].
This commentary elaborates on how such a measure of severity should be validated to determine whether it is appropriate for practical use.
Theoretically, this will probably imply accepting that understanding is always of dialogical nature, and therefore can never be pinpointed to an empirically "simple" objective measure, such as a tick box in a survey – but that would also lead to the question of whether the survey method is the most appropriate to validate an SRR.
Biomonitoring studies should follow validated protocols that are appropriate to the matrix and analyte(s) of interest.
To move the quality of our tools forward it is therefore appropriate to reflect and validate popular assumptions usually applied in computational approaches.
Finally, large-scale human epidemiological studies are appropriate and will be needed to validate and identify nongenetic factors that increase HSCR risk.
Hence, it is important to develop and validate appropriate self-reported OHRQoL measures for very young children.
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