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In fact, given that the distance between SNPs with a polymorphic indel between them is on average shorter than the distance given in the databases (an indel in the Seattle SNPs and NIEHS databases is always represented by the long indel variant regardless of whether it is an insertion or a deletion), we underestimate the recombination rate.
To determine the direction of the indel, namely whether it is an insertion or deletion, we firstly need to know the ancestral state of the indel.
First, indels are classified into categories based on three properties: (1) whether it is an insertion or a deletion, (2) the affected nucleotide length, and (3) whether it disrupts the protein translation reading frame.
Similar(57)
It's an insertion of Western modernism into China".
HCC: It is a caching insertion policy based on the social relations with the mobile user.
PCP: It is a caching insertion policy in NDN to reduce the service disruption time due to the content provider mobility.
ICC: It is a caching insertion policy used in multi-hop wireless networks which only stores those contents that would be of possible interest for the corresponding user according to the social distance which is defined as the Euclidean distance of the user u and the content c.
Since an insertion in one sequence can always be seen as a deletion in the other one, when a gap is used in the query sequence, it is a gap insertion; otherwise, it is a gap deletion.
While the flanking sequences were conserved in these two other marsupial species, we did not find the sequence immediately around the precursor, suggesting that it is a recent insertion in tammar.
It is a targeted insertion rather than random integration of 350 bps from Alu Ya5 subfamily into the exon 3 of BRCA2 gene leading to its deletion and consequent loss of transactivation domain.
"His entry now is an insertion of new interest and energy in the campaign as a whole".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com