Sentence examples for it is a substantial challenge from inspiring English sources

"It is a substantial challenge but it is one in which groups around the world have been making a lot of progress in the past few years," partly thanks to new tools for shutting off genes and analyzing gene-protein interactions, says Broad computational biologist Aviv Regev, who will head the observatory.

It is a substantial challenge to fairly represent this uncertainty in a Monte Carlo analysis.

"It's a substantial challenge for Ratner to finish this project within the time frame he's proposing.

"It's a substantial challenge, but I've always felt that she has the ability to do it," Nicks said.

There is a substantial challenge facing views such as Reid's.

These days, there is a substantial challenge to this model from students and younger workers in the workforce who hold very different values than previous generations.

Understanding the design principle of reward functions is a substantial challenge both in artificial intelligence and neuroscience.

Respecting a wide range of worldviews while increasing acceptance of biological evolution as the scientific explanation for the origin of species is a substantial challenge that may be difficult to achieve.

Performing modal tests on wind turbine structures over 100 m tall is a substantial challenge, which has inspired innovative developments in modal test technology.

Particularly, the turn-around time that is, the time needed to switch from receiving (transmitting) to transmitting (receiving) should be very small, which is a substantial challenge to hardware design.

There is a substantial challenge for farmers, agronomists and others to identify and assess suitable new systems and to bring the public into the debate and into the solution.