It is a complex process that involves numerous factors: hormones, growth factors, vitamins, and cytokines, and notably osteoprotegerin (OPG) and receptor activator for nuclear factor-κB (RANK) ligand.
The control of mRNA stability is a complex biological process that involves numerous factors, including microRNA (miRNA) and short interfering RNA (siRNA).
Besides, autophagy is an extremely sophisticated system that can be activated through different signal pathways and involves numerous factors.
Therefore, gene ontology analysis of differentially expressed proteins involves numerous factors that are involved in these processes, among them, 12 proteins with a difference over 1.5-fold (Student's t-test, P < 0.05).
Now it is recognized as a more dynamic, complex disease involving numerous factors affecting the whole joint [ 4].
Coronary heart disease appears to develop through multiple pathways, whose association with cardiovascular risk is mediated by complex processes involving numerous factors ranging from genetic predisposition to unfavorable socioeconomic circumstances.
Though the history of Italy's winemaking revolution is a complex one, involving numerous factors and a variety of key figures, considerable credit goes to Angelo Gaja, a dynamic visionary with utterly uncompromising standards, a first-rate century-old family winery, a savvy gift for marketing, and a tireless thirty-year commitment to promoting both his own wines, and those of his country, abroad.
The process of aging is complex involving numerous factors centered on transcriptional changes with advanced age.
It involves numerous nonlinear processes.
However, the abrasive behavior of WC materials is very complicated because they are formed from several phases and their damage mechanism involves numerous parameters and factors that may be related to the composites themselves and the external environment.
However, unlike the myotome, cardiomyocyte differentiation involves numerous cardiogenic transcription factors acting in concert.
