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Notably, the recognition of T cell antigens by the αβ TCR is unique among receptor-ligand interactions as it involves engagement of a 'co-receptor' molecule that binds to the MHC at a largely invariant site distal from the TCR-docking platform 3– 5.
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It also involves engagement on issues that span the foreign-domestic divide, including in the economic, energy and immigration realms.
It also protects much of the business on the Net, which involves engagement with regular people.
During the last few years it has become evident that the first contact of an invading microbe with the host cell involves engagement of TLRs and other PRRs with microbial molecules inducing an innate immune response.
For Heidegger, the very Being of the individual involves engagement with the world.
The second step involves engagement of the latter receptor by IL-2 which, in the experimental setup used by these authors, was not derived from the same stromal cell (Lio and Hsieh, 2008).
Learning cognitive concepts, such as STEM (science, technology, engineering, and mathematics), involves engagement, attention, interaction, and mastery of information, generally through the guidance of a teacher in formal learning environments.
Available evidence suggests that the inflammatory process involves engagement of Toll-like receptors and activation of the complement cascade by degradation products of extracellular matrices of cartilage and other joint tissues.
But diplomacy inevitably involves engagement, and sometimes socializing, with more or less unsavory foreign leaders.
Platelet activation is an essential component of hemostasis and thrombosis, and involves engagement of complex signaling machinery.
Eligibility: Demonstrating compliance with national sustainable development rules involves engagement with the national authorities and providing evidence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com