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In other words, besides the pre-defined objective in interest, we will not know if a perturbation triggers collateral influences on other parts of the system and what it implicates to the overall system.
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It is implicated to mark stem-like cells of various tissues and cancers (reviewed in Mizrak et al, 2008).
Therefore it was implicated to apply the 33% percentiles as cut-off points for R0 patients according to their mRNA expression levels, i.e. for PAI-1 (33% percentile: 0.228) and for uPAR-del4/5 mRNA expression (33% percentile: 0.001).
Finally, it is concluded that the interaction effects between different lifting parameters must be considered in addition to the effects of individual lifting parameters for further research as it implicates potential modifications to the currently recommended weight load estimation procedure.
It is also implicated to play a role in several cancers, metabolic and neurodegenerative disorders.
Furthermore, it has been implicated to be involved in the pathogenesis of diabetes [3, 4] and inflammatory processes in the gut [5].
It has been implicated to have a potent anti-inflammatory role in several autoimmune disease models, including CIA [ 5].
Interestingly overexpression of STK17A has been reported in other cancers like glioblastoma where it has been implicated to correlate to poor prognosis in those patients [ 52].
It has been implicated to be a tumour-suppressor gene in studies on nasopharyngeal, oesophageal, breast, colorectal, cervical, lung and hepatocellular carcinoma cell lines.
Callose accumulation was also evaluated (Additional file 1B) as it was previously implicated to have an important role in virus spread [ 17– 17].
It has been implicated to play a crucial role during the aging process for several reasons (Guarente and Picard 2005; Mahlknecht and Voelter-Mahlknecht 2009a; Saunders and Verdin 2007; Voelter-Mahlknecht et al. 2006b; Westphal et al. 2007).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com