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It has well been documented that the cytokine IL-12 plays a pivotal role in Th1 polarization [13], [15].
It has well been recognized that genes play a central role in directing each of these programs to determine the growth rate and final size of the seed [2] [6].
It has well been known and studied that male and female differ markedly with regard to their use of, and responses to, METH and related amphetamines [ 29].
It has well been established that stromal tissues surrounding cancer cells, such as fibroblasts, inflammatory cells, and vascular endothelial cells, are deeply involved in tumor progression.
It may has well been J. Crew's last catalog.
Three runs for Boston; it might've well have been 13.
"With Steven it has been well documented that we're looking after him.
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