Sentence examples similar to it has substantially changed from inspiring English sources

However, the entry was pushed back until it was finalized during the latter part of the fifth season; according to supervising producer Adam Muto, by the time the episode was being developed during the fifth season, it had substantially changed.

Qunar started out in 2005 to be the "Kayak of China," but has substantially changed its model, because the online inventory just isn't there yet in China the way it is in the US.

Correspondents say Moscow has substantially changed its position on the issue over the past two weeks - during which time Russia has been hosting the Sochi Winter Olympics.

Denmark has substantially changed its primary care referral procedures since the latest reported comparative survival figures.

ART has substantially changed the face of HIV infection where it has been successfully introduced.

Chemical engineering has substantially changed the human civilization through its services and products to improve the quality of life for human being.

While relapses are frequent, and expected in Janet's work, the situation has substantially changed.

The role of fisheries management has substantially changed over the past several years.

Experimental results indicate that the increase in growth speed has substantially changed the twinned morphologies.

The departure of such hard-edged, liberal aides as Harold M. Ickes and the politically ambidextrous consultant Mr. Morris has substantially changed the tone and volume of debate.

The advent of the Bcr-Abl selective tyrosine kinase inhibitor imatinib mesylate (Glivec, Gleevec, Novartis, East Hanover, NJ) has substantially changed the treatment landscape for chronic myelogenous leukemia (CML).