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Moreover, his work stimulated further development of both the intuitionist and the formalist schools of thought in the logical foundations of mathematics; it has substantially altered mathematical education in the United States and is often associated with the "new mathematics".
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*Yes, I know I have substantially altered the original title of the philosophy, but some fudge is given when it comes to standard rules and practices.
His comments suggest that the Foreign Office has substantially altered it priorities since Philip Hammond was appointed as Foreign Secretary last year.
As there were only 18 such women (6 pre-TC, 12 in TC era) it is unlikely their exclusion has substantially altered the overall study results: however, is a further reason why a randomised trial would be the preferred method of demonstrating utility of a multiple pregnancy clinic Vs. standard care.
Human influence on the landscape has caused nutrients in surface waters to increase to the point where their presence has substantially altered biological communities.
In recent decades the Chinese financial system has undergone dramatic restructuring, which has substantially altered the country's mutual and co-operative financial institutions.
String theory has played a highly influential role in theoretical physics for nearly three decades and has substantially altered our view of the elementary building principles of the Universe.
The development of waterways, for hydropower and other industrial uses, has substantially altered many of the freshwater habitats of the planet and this has had considerable impact upon aquatic organisms.
"Every once in a while in the history of mankind, a book has appeared which has substantially altered the course of history," Senator Ernest Gruening, a Democrat from Alaska, told Carson at the time.
Therefore, the absence of sediment-rich floods in this regulated river, which formerly deposited large fluvial sandbars from which aeolian sediment was derived, has substantially altered processes by which the prehistoric, inhabited landscape formed, and has also reduced the preservation potential of many significant cultural sites.
At the same time, the comments made by the adviser, Eric Fehrnstrom, will serve to remind voters of a major issue in the campaign: that Mr. Romney has substantially altered his positions on a wide range of issues since he ran for governor in Massachusetts in 2002.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com