Sentence examples similar to it has posed considerable problems from inspiring English sources

By only using SNPs with the rarer allele observed at least twice, a misidentification of SNPs due to sequencing errors should not have posed considerable problems as the overall sequencing error rate (including both, indels and base substitutions) is only 1.07% for 454 GS FLX [ 39].

In doing so it has posed considerable challenges to how we assess and prevent harmful chemical exposures.

While it may be confusing to some folks, it has posed no problems.

The large amount of repeated sequences posed considerable problems in the assembly of SLY.

69 This poses considerable problems for those seeking to encourage networked behaviours and collaborative structures.

The exhibition has posed logistical problems.

Rawls' "moral powers" condition has posed further problems.

Telling Booth's story has posed significant problems for historians.

Quality has posed even greater problems.

Needless to say, this language has posed problems for translators, who usually have to choose between conveying the literal meaning of the Greek -- crucial to understanding tragedy's intellectual and moral themes -- and its considerable poetic allure.

But this subject matter and her approach to it seem to have posed a problem for many critics.