Sentence examples for it has markedly changed from inspiring English sources

With the first round scheduled for Thursday, the scene there is nothing like it was in 1964, when the club hosted its first United States Open, and it has markedly changed since even 1997, when it hosted its second.

The business of tending teeth has markedly changed in a generation or two, dentists say.

During the past ten years, however, the situation has markedly changed.

The landscape for management of IPF has markedly changed with the advent of approved therapeutic options for IPF.

A heavy influx of families and non‐manufacturing in dustries — largely from met ropolitan New York and Newark — has markedly changed the character of the Hightstown area since the early 1960's.

At that time, the arrival of the first biotech drugs has markedly changed the landscape, requiring a completely new approach to pre-clinical development.

But in the subsequent 33 years, the media landscape has markedly changed, causing several justices to question in recent decisions whether those standards were still relevant in a world of unfiltered cable television, Internet, film and radio.

The landscape of clinical trial design has markedly changed in recent decades, with a clear emphasis on streamlining drug development towards specific patient populations and indications for investigational agents.

Over the past genomics has markedly changed our view on core-promoter organization [ 1].

The management of neovascular AMD has markedly changed over the past decade.

Combination antiretroviral therapy (cART) has markedly changed the prognosis of HIV-infected patients, reducing AIDS-related morbidity and mortality [ 1].