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Although it has been frequent practice in genome sequencing studies of familial disorders to exclude all previously observed variants (both rare variants and polymorphisms), it is our perception that the rapidly growing collection of genome sequence data and variants makes it increasingly likely that such screens will exclude relevant causal mutations.
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Since the restaurant was founded in 1942, it has been frequented by film stars - as the wall-photos prove.
What that research has shown is not that wars between nondemocracies, or between democracies and nondemocracies, have been frequent; instead, it has demonstrated that, although interstate war is a rare event in general, wars between democracies have been even rarer.
If it is the case that extinctions have been frequent, then what we are actually reconstructing with the mtDNA sequence data, is the evolution of the species on the island complex during the last 2 Ma, using as a starting point some more recently derived haplotypes of the ancestral stock.
Asymmetric shocks have been frequent.
Security scares have been frequent in Kabul.
The assaults have been frequent.
Protests have been frequent since Mr. Hariri's assassination.
Such policies, when adopted, have been frequent targets of criticism.
Kerry and Zarif's telephone contacts have been frequent.
Frank Shields and Honeychile (Patricia) Wilder have been frequent guests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com