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A big hurdle: Using silicon (which requires a clean room) is expensive; its rigidity makes it hard to devise microscopic valves that won't leak.
That uncertainty makes it hard to devise a public-health message that strikes a balance between comfort and terror.
The difficulty in choosing a model for heritability H makes it hard to devise an unambiguous definition for H. Thus, any estimate of predictive accuracy should be taken only as a rough indication of precision.
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This points to a problem with the Clean Air Act: it separates acid rain, smog and other effects of nitrogen oxide pollution, making it harder to devise good environmental laws and harder to gain political support for them.
Members of Congress say it is hard to devise a new department without knowing the strategy it is meant to pursue.
So it is hard to devise accurate models.
The problem is that it's hard to devise experiments to test this, said Eric J. Johnson, a psychologist at the Columbia Business School who was not involved in the study.
Our main concern is that it is hard to devise an appropriate control here.
As the professor of dance history and criticism Mindy Aloff recently put it, "it's very hard to devise the step-by-step logic to tell a story coherently.
It would be hard to devise a more wasteful, damaging, unsustainable system.
It would be hard to devise a surer formula for economic catastrophe.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com