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The inhibitor has a distinct mechanism of inhibition; it gains potency and specificity through interactions with the protease surface loops, and inhibits by binding in the active site in a catalytically non-competent manner.
While the notion of damage wrought by petrochemicals and the chain of consumption is not a new one, it gains potency with images of swamps fenced off as toxic waste sites and maps depicting the spread of dead zones as channels dug for oil pipes funnel saltwater into freshwater wetland systems.
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Taiwan is a big unfinished nationalist project at a time when Chinese nationalism is gaining potency.
Despite Virginia providing a wrench in the notion the South is turning more conservative with more Americans heading toward the Sun Belt, let's just assume for the moment the argument is true and red Southern States did indeed gain potency with the new Census numbers.
Systematic modifications of 39 were carried out to gain potency and reduce molecular weight and lipophilicity.
Unlike ICEC-0229, ICEC-0782 was found to gain potency towards CDK2 and CDK9, while remaining active against CDK7 in the nanomolar range.
Hence, the inhibitory potency of FIIN-2 may be significantly improved by derivatizing it with an aromatic ring such that it gains the ability to engage this hydrophobic pocket as it occurs in the FGFR4K ponatinib structure.
It gains new words.
It gains more respect.
According to Peiperl and Baruch ([1997]), in a post corporate career realm, vocational identity gains potency and serves as a source or predictor of workplace identity.
It gained speed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com