Selective pressure for high DGR activity might decrease once the target protein is well adapted to its function, thus fixing it in the genome with a normal mutation rate.
In particular, it is not clear to what extent the mutations in ESA1 impair its function thus rendering its role in DNA replication far for from being excluded.
Under current regulations no CO2 emissions are attributed to combustion of biomass, thus it functions as a zero-carbon fuel.
A key concept with high degree centrality is able to activate many other key concepts; thus, it functions as a hot topic's central key concept [54].
Interestingly, the Arabidopsis AtMYB12 does not contain an R/B-like bHLH binding motif, thus it functions independently of a bHLH cofactor [ 48].
Thus, it functions as a bridging and stabilizing molecule between the Sin3 complex and corepressors such as N-CoR [ 4] and CIR [ 5], and DNA-binding transcription factors such as YY1 [ 6].
It is well known that the caput epididymis requires higher androgen level to maintain its morphology and functions, thus it seems likely that more cells undergoing apoptosis might occur as a consequence of impaired androgen action.
Moreover, the software agents in a system are often divided into various groups, and each group contains the agents undergoing similar tasks or having related functions; thus, it is necessary to find the influential agent group (not only the influential individual agent) that can influence the system outcome utilities more than the others.
Notice that φ ( a, ⋅ ) is the limit of a monotone increasing sequence of continuous functions, thus it is lower-semicontinuous, likewise φ ( b, ⋅ ) is an upper-semicontinuous function.
Additionally, lithium is known to cause alterations in various organ functions, thus it merits a regular monitoring.
The E2F family members display partial redundancy as well as antagonizing functions; thus, it is challenging to elucidate the functions of individual mammalian E2Fs.
