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The way that summary judgments of risk of bias are reached should be explicit and should be informed by empirical evidence of bias when it exists, likely direction of bias, and likely magnitude of bias.
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Therefore, the 23rd gene, if it exists, is likely to have a shorter than average CDS length otherwise its existence is less likely.
The lack of clearly consistent findings, however, might also be an indicator that such a risk, if it exists, will likely be low and of questionable clinical relevance.
The hospital is located relatively close to major roads [ 8], hence this type of selection bias, if it exists, would likely only underestimate the results.
Although our data clearly show that a Cassini protein can be made, the product, if it exists, is likely to have unusual characteristics as is demonstrated by the migration abnormalities and aggregation of EGFP-Cassini after heat treatment in SDS-SB lysates (Additional file 5: Figure S5).
An annoying and assuredly small underclass of the poor also existed: likely, persons "destroyed" by drugs or alcohol.
The risk, if it exists, is therefore likely to be more pronounced on the left side.
Although no figures are available on premarital sex from this community anecdotal evidence suggests that even if it exists it is likely to be very rare.
However we did not detect PDC activity in cell extracts (<0.005 U/mg), so this activity (if it exists) does not likely play a significant physiological role.
The ultimate aim is to conduct a study that is large enough to ensure that an effect of the size expected, if it exists, is sufficiently likely to be identified.
Although there are no experimental data regarding the SpoVS oligomeric state we supposed that it might exist, like Alba and likely its most closely related families of relatives (Aravind et al., 2003), as a dimer, a hypothesis supported by the presence in the dimer model of a large hydrophobic interface between the subunits.
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