It also excluded possible mutations that would lead to amino acid changes in KCNQ1, HERG, and LAMIN A/C commonly associated with LQT1, LQT2, and DCM with conduction disorders on earlier occasions.
No antagonist altered BiFC alone, but while this eliminates biased efficacy towards β-arrestin2 recruitment, it does not exclude possible inverse agonist properties.
This may suggest that COMP and GEP are independently active in different regions of the atherosclerotic plaque, although it is not excluding possible interactions during the early stages of plaque development.
Third, sputum cultures for organisms other than mycobacteria were not done, making it difficult to exclude possible concomitant pyogenic infections leading to suppurative lung disease and bronchiectasis, which could by itself cause finger clubbing.
At the same time it excludes another possible source of the particles: random cosmic events like exploding stars, which would not be so uniformly distributed, at least not over a period as cosmically brief as 1½ years.Unfortunately, more data are needed to rule out a third possibility: that the observed particles were created by pulsars, the remnants of these stellar explosions.
Given the surprising result of this experiment, it was paramount to exclude possible trivial artefacts due to the way the experiment was designed.
In order to investigate the role of CRP in the immune response, several papers previously indicated that it is necessary to exclude possible pro-inflammatory artefacts due to the contamination of CRP commercial preparations.
Re-analyses were also performed after excluding possible cross-transmission.
First, we exclude possible external pressure effects during freezing.
However, it does not exclude the possible influence of those cytokines on prevention of the colitis induction at earlier time point.
