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Photodynamic therapy is an expensive treatment that entails substantial risk and inconvenience.
The high incidence of injury in rugby union, influences team performance and entails substantial treatment costs.
First, production entails substantial fixed costs; and second, preferences differ across groups of consumers.
As with any application of force, however, use of the oil weapon entails substantial risk.
However, it will also entail substantial shifts in production systems, as when annual row crop production shifts to perennial biofeedstock production.
The tape is almost certain to strengthen America's resolve to pursue the campaign against the terrorists, even if it entails a substantial deployment of ground troops to root out Al Qaeda leaders from the Tora Bora caves.
A violation is deemed "serious" when it entails the "substantial probability that death or serious physical harm could result from a hazard about which the employer knew or should have known".
Also, he knew that a replacement engine would entail substantial redesign work to the aircraft, and it'd probably send the price over the $1 million mark.
Both moves typically entail substantial new R&D and marketing capabilities and are fraught with risks.
The analysts added that the potential deal would likely entail "substantial" cost savings over three years.
Finally, the process of optimization is not necessarily efficient and may entail substantial trial and error.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com