It can either stimulate or inhibit proliferation, and either stimulate or inhibit differentiation, thus playing an important role in connective tissue as well as in the healing process, including tendon repair (Atamas 2002).
Adrenergic signalling can exert opposing influences on astrocytic glycogen metabolism: it can either stimulate glycogen degradation by increasing cytosolic Ca2+ or cAMP, or inhibit degradation by inhibiting cAMP production.
Therefore, it is possible that this intervention either stimulates tissue regeneration or changes the character of the COMP fragments released from the tissue.
It can also either stimulate or inhibit NF-κB activation depending on the concentration, exposure time, and cell type (Harris and Shi 2003).
Depending on the cell growth substrate FGF either stimulates endothelial cell growth or promotes capillary differentiation.
Generally, the actors feel that their business format mainly either stimulates the achievement of positive results or has no impact.
Chloroquine elevates the pH of vesicular compartments (Cotten et al, 1990), and either stimulates or inhibits the efficiency of endocytosis-mediated gene transfer, depending on the delivery vehicle.
An increase in KATP-channel activity either stimulates or inhibits glucagon secretion, depending on the magnitude of the increase in the KATP current.
The myokine appears to inhibit muscle progenitor cell proliferation in all systems, although studies with mammalian cell lines and primary fish myosatellite cells suggest it either inhibits or stimulates differentiation, respectively [ 7- 11].
It has been reported that T cells, either stimulated with anti-CD3 and/or anti-CD28 or left unstimulated, do not express IL-1F8 mRNA, whereas lipopolysaccharide-treated monocytes do [ 10].
