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But it does, bound by a crunchy, golden crust.
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This protein has no ligand binding domain of its own, but it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer [ 36].
This protein has no ligand-binding domain but it does bind tightly to other ligand-bound EGF receptor family members enhancing kinase-mediated activation of downstream signaling pathways.
Although Mdm4 itself does not have an intrinsic E3 ligase activity toward p53 (Linares et al., 2003), it does bind to p53 transactivation domain to block its transcription activity (Shvarts et al., 1996).
Although dnCaMKIV cannot bind to ATP, it does bind to Ca2+/calmodulin.
The results demonstrated that p300 does not bind to WRN488 1432 (Fig. 6B, upper panel, lane 2), but it does bind to WRN239 499 (Fig. 6B, upper panel, lane 1).
Although Adr1 is not the dominant factor at this gene in terms of expression, it does bind to this promoter [9] and has a minor affect on expression.
If it does bind to RNA it is probably not through the RBD since structures of the complex show that this domain forms an unusual protein-protein interaction with Magoh [14] [16].
HSP70 is a less studied protein in CF; however, it does bind CFTR.
HIP1R does not seem to bind AP2 directly but it does bind to Clathrin albeit with much lower affinity than HIP1.
11 Importantly, INSL5 does not activate RXFP3, however, it does bind to the receptor with low affinity and can act as a weak antagonist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com