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However, technical challenges have made it difficult to image the brain during multijoint lower limb movements like those involved in locomotion.
Previously reported genetically engineered mouse models that mimic human APC gene mutations mainly develop adenomas in the small intestine (e.g. ApcMin model), rather than the distal colon, making it difficult to image the progression of polyps in vivo using small animal endoscopy.
On bare mica surface, all molecules of the α3β3 subcomplex rapidly diffused on the surface, which made it difficult to image them clearly.
However, the thickness of these layers can be as thin as 3 15 μm [ 6], which makes it difficult to image them reliably in vivo.
The same pPGEK-expressing cells also showed the network pattern of the ER; however, the fluorescence intensity within the ER was fainter than the densely-packed, very bright spherical structures, making it difficult to image both simultaneously.
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If Yahoo! is unwilling to put a stake in the ground over search, it's difficult to image what part of its business it regards as worth fighting over.
So while it is difficult to image a nanocluster in the imaging mode, SAED measurements can be useful for the analysis.
Although the circular pits of some hundred nanometers could be seen via SEM imaging, it remained difficult to image primary titania particles.
With currently available imaging technologies, it is difficult to image the fine moving structures such as valve leaflets and chordae tendinae with the image quality sufficient enough for 3D printing.
It is difficult to image deep into cells with single-molecule imaging techniques.
So far, since it is difficult to image the electron trajectory on an event-by-event basis with scintillation imaging detectors, the developed system will be a new and useful tool in radiation detection and measurements.
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