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In many cases this has demanded substantial effort since many NGS software applications are not prepared to run on multi-user, multi-project HPC systems.
Informal caregiving demands substantial effort, productive time and financial resources of caregivers.
However, CDPT demands substantial time and effort from patients to maintain these benefits; the treatments are not always well-accepted, and patients may suffer from a deterioration in quality-of-life or a time-dependent loss of initial treatment benefits.
Managing these relationships demand substantial more effort than stationery contracts.
No doubt, such projects demand substantial fundraising efforts, take a long time to build and require intensive coordination by multiple agencies.
Tailoring existing fire spread models to particular landscapes is challenging because it demands a substantial data collection effort.
So it demands more effort on our part to educate our colleagues.
From 2003 to 2008 it sued thousands of file-swappers, demanding substantial damages from individuals in years of litigation.
However, Republicans made it clear at the three-day meeting that they intended to demand substantial spending cuts in return.
The patients' rights bills would demand substantial record-keeping.
Even though a traditional metal ceramic restoration is still popular, it demands both time and effort.
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