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Poor solubility creates major obstacles for formulations and successful chemotherapy with ethaselen.
But national security officials from both the Bush and Obama administrations say such a ban would create major obstacles to swift punishment of terrorism suspects.
Opponents say the changes create major obstacles to patients who want to get the drug and cut the number of locations where it would be available.
Human Rights Watch research on the justice system in South Sudan underscored the system's deep limitations that would create major obstacles to fair, credible cases involving the most serious crimes.
First, unfettered social and cultural acceptance of IPVAW may not only lead to abetting such practices, but may also create major obstacles toward altering such practices.
It is also noted here that there were several other information fields e.g. name of mother, age of mother, address, which were either not recorded or recorded partially, or even recorded differently in different registers, which created major obstacles in the ensuing matching task conducted to develop the pregnancy cohort.
"It creates major uncertainty," Mr. Odenius said.
It created major delays for riders.
It created major division.
"Politically, it creates a major obstacle to Trump and Congress' ongoing efforts to change or replace the law.
Such fragmentation creates major practical obstacles for investigators attempting to develop partnerships and teams with diverse expertise [ 1- 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com