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So when an athlete or a businessperson veers off course, it can create a substantial setback — one that could take years to recover from, if at all.
And yet, somehow, it creates a substantial, fully imagined world as convincingly as Creech's longer, earlier books.
It did not create a "substantial risk of serious physical injury".
"That was a substantial setback for Vitro and a substantial victory for the holdouts".
While these tactics conformed to the national government's political priorities, they were a substantial setback for municipal Shanghai's global aspirations.
Fibrosis poses a substantial setback in regenerative medicine.
It is sometimes assumed that a general election must create a substantial disturbance to trade.
The armchair he painted for Gauguin is more substantial, with a gaslight behind it creating a mysterious, nocturnal effect.
Instead, it creates a sense of self-worth because it leads people to genuinely care about their own well-being and recovery after a setback.
Population explosion has created a grave setback in the economic growth and all-round human development in developing countries.
The launch alliance hasn't seen a single major failure since it was created a dozen years ago; SpaceX has lately been averaging a major setback every year.
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