No information is available about the bioactive conformation of Kalydeco however due to its relative rigidity a reasonable pharmacophore model could nevertheless be proposed.
This seems a highly improbable outcome for Goldman but the damage to its reputation as a result of the S.E.C. case could nevertheless be costly.
They could nevertheless be constitutive of using an expression with the determined meaning insofar as it would be impossible to so use the expression unless the prescription was in force for the speaker.
This property is a drawback for nucleation but could, nevertheless, be exploited when the excess of nucleation, rather than the lack of it, is a problem and cannot be controlled by any other means.
"This drop in French supplies could nevertheless be compensated by the likely return of Russia and Ukraine on the export market," it said.
The state could nevertheless be competitive, particularly if Mr. Obama's overall standing deteriorates.
Hammond-Stroud's Alberich was also richly drawn, deploying incisive enunciation that could nevertheless be varied to dramatic effect.
Two others — Michael DeBakey and Christiaan Barnard — saved lives by other means, showing that a heart that could not be mended could nevertheless be replaced.
Such expectations "are ridiculous," he said, but added that certain players could nevertheless be affected by them.
Bob Arum, the wily dealmaker whose company, Top Rank, promoted De La Hoya, knew that a niche sport could nevertheless be a profitable one.
