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After CAR release, it could exert its antimicrobial activity on microorganisms, adherent or not, that are in its surrounding environment.
Many reports indicate that the inhibition of GSK-3β reduces ischemia/reperfusion cardiac injury through the regulation of the mPTP opening, indicating that it could exert its functions by modulating mitochondrial activity [29] [32].
Given YKS's stress-modifying capabilities, we hypothesized that it could exert its effect by impacting the HPA axis, and more specifically, by regulating GR expression in the hypothalamus.
Since tirilazad does not penetrate the BBB effectively, it is found mainly in the membranes of endothelial cells, where it could exert its action.
Although T2 has poor affinity for thyroid receptors, it could exert its transcriptional control through cell surface receptors that are also known to respond to TH [ 5, 18, 60], or through reversible epigenetic modifications to histone complexes [ 61].
Although it is mainly localized at the vacuolar limiting membrane, consistent with its TORC1-related function, Sch9 is also associated with chromatin where it could exert more direct effects in the control of transcription factors like Gis1 (Pascual-Ahuir & Proft, 2007).
Similar(30)
I wanted so badly to believe that I could go it alone and that I could exert control over my body and my disease.
I became an anorexic for the reason most women do, because I felt it was the only semblance of control I could exert in my life.
If CD does enter the brain, it presumably could exert its impact on cholesterol and GSL accumulation by acting at the plasmalemma of brain cells or after being internalized.
While NAC may serve to diminish binaphthoquinone cytotoxicity by neutralizing ROS through increased glutathione production, it also could exert its actions by interacting directly with binaphthoquinones or their derivatives to reduce their cytotoxicity [13], [25].
The governor of the Bank of England had almost papal powers and, it was said, could exert authority by arching an eyebrow.
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