A presumptive identification and susceptibility profile was obtained at 4 hours, based upon which the investigators recorded a decision as to whether the patients' antibiotics could be escalated, de-escalated or remain unchanged.
The study design allowed for sunitinib a dose escalation to 50 mg and de-escalation to 25 mg, whereas the initial dose of irinotecan could be escalated to 300 or 350 mg m−2.
However, the recovery in GP results could be escalated up to 96% after only a month through proper material design and conditioning.
At the investigator's discretion, efalizumab could be escalated up to 4 mg kg−1 weekly.
This dose could be escalated without major toxicity to 70 mg m-2 week-1.
Pirtrexim was generally well tolerated, in eighteen patients the dose could be escalated.
In contrast, if ifosfamide is continuously administered over 3 days, pazopanib could be escalated to dose levels exceeding the registered single agent dose of 800 mg daily.
Provided radiation doses to normal tissue were acceptable, the radiation dose to the primary thoracic tumor could be escalated to 72 Gy.
In 2005, the Northern Norway Regional Health Authority initiated a review to clarify which telemedicine services could be escalated into large-scale use.
For months 3 15, the dose of efalizumab could be escalated to 4 mg/kg per week for up to 4 weeks if clinically indicated, then maintained at 2 mg/kg per week.
