Sentence examples for it could be downstream from inspiring English sources
However, due to redundancy of these pathways we cannot point to the specific type of cells that are involved in the development of disease: it could be downstream mechanisms with T helper cells as primer players, or upstream mechanisms related to antigen presenting cells, B cells, macrophages/monocytes or dendritic cells.
Since the downstream effects of PKA could be blocked by dominant-negative Rac1 [ 37], and because Rac1 is a direct activator of Pak1, it is tempting to speculate that Pak1 could be downstream of PKA in affecting the function of the ER.
It is important to keep in mind that the integrated cassette "ter rgnB – (genes of interest) – tL3" could be downstream from a native transcription unit in the chromosome.
Interestingly, our own data indicate that these factors could be downstream targets of mitochondrial activity.
Interestingly, western-blot analysis revealed that PPARδ is strongly expressed in quadriceps muscle extracts from transgenic mice thus suggesting that PPARδ could be downstream targets of mitochondrial activity.
Because miRNA inhibitory effect is at posttranscriptional level, the most significant changes could be downstream genes of the miRNA target at transcript level.
In addition, we found that PGC-1α and PPARδ, two major regulators of muscle phenotype were up regulated in p43 transgenic mice suggesting that these proteins could be downstream targets of mitochondrial activity.
Importantly, 12 other cytokines are in the IFNγ pathway and could be downstream modulated by this cytokine.
Moreover, we show that the rescue of Purkinje cell dendrites and dendritic spines by HMGB1 could be downstream effects.
In contrast, in slices from immature animals (less than postnatal day 20), MOPr desensitization was observed to be heterologous and could be downstream of the receptor.
