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For this, the soil isotopic module was extended to take into account plant water uptake by roots and the model was modified so that it could be constrained with collected input data (e.g. ET flux).
Based on early estimates of the mutation rate in humans and the size of the human genome, simple calculations done decades ago showed that only a small fraction of it could be constrained at the sequence level, otherwise there would be too many deleterious mutations in every generation for the species to survive (Ohno 1972).
It could be constrained to one dimension of motion by the use of oligomeric "fences".
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Next, it was tested whether estimates could be constrained to be equal for twins rated by the same and by different teachers.
It was suggested that this trend could be constrained by the elimination of the two extremes through suppression [ 30] or repetition [ 33] of complete rounds of macronuclear DNA synthesis between each cell division [ 34].
But it also notes that without external inspectors schools could be constrained by the skills within their team and creating a peer review system that's sufficiently challenging can be difficult.
It was further tested whether the twin correlations could be constrained to be equal across sex (MZM = MZF and DZM = DZF = DOS).
"It's possible that some of the SA batsmen – du Plessis, de Villiers, Amla et al – could be constrained by the need to produce a match-saving innings to give themselves a batter chance of succeeding Smith," says John Starbuck.
Nadathur could be constrained by the fact that many of its investee companies are located in Bangalore, therefore they can't access entrepreneurs in, say, Calcutta or Delhi," says Deshmukh.
For example, if a locus has evolved some form of dosage compensation, such that the current monoallelic expression is close in its level to the ancestral biallelic expression, then reversion to biallelic expression could be constrained.
The only way he could be constrained was by living apart.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com